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The Conditioning Human Initiation of Transcendence Age was initiated by Manageficient Enterprises thanks to their patented DNA editing technology. The CEO was obsessed with Taylorism, the theory of breaking down worker tasks into individual components that anyone can learn.
This initiated the DNA modifications in the lower classes, making them functional, while the upper class enhanced their beauty, intelligence, and strength. Their injections altered the human DNA so drastically that they were no longer similar.
Some lower classes were not altered into the Post-human Workers and remained unmodified and birthed the rebellion against the unified world known as The Society.